Steroid responsive inflammatory conditions of the palpebral & bulbar conjunctiva, cornea, & anterior segment of the globe eg, allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitis, when the inherent hazard of steroid use is accepted to obtain an advisable diminution in edema & inflammation; corneal injury from chemical, radiation, or thermal burns, or penetration of foreign bodies.
Known or suspected hypersensitivity to prednisolone & other corticosteroids. Viral diseases of the cornea & conjunctiva including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella. Mycobacterial infection & fungal diseases of ocular structures.
Upon prolonged use, risk of glaucoma w/ damage to optic nerve, defects in visual acuity & fields of vision, & in posterior subcapsular cataract formation; immune response suppression; corneal & scleral thinning leading to perforation; fungal infections of the cornea. Acute purulent infection may be masked or activity enhanced. Routinely monitor IOP if used for ≥10 days. Use w/ caution in the presence of glaucoma. The use of steroids after cataract surgery may delay healing & increase the incidence of bleb formation. May prolong the course & may exacerbate the severity of many viral ocular infections (eg, herpes simplex); frequent slit lamp microscopy is recommended. Not effective against mustard gas keratitis & Sjogren's keratoconjunctivitis. Discontinue use if inflammation or pain persists longer than 48 hr or becomes aggravated. Pregnancy & lactation. Childn.
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